Journal article

A Systematic Review and Meta-Analysis of Predictors of Response to Trauma-Focused Psychotherapy for Posttraumatic Stress Disorder

Dharani Keyan, Nadine Garland, Jasmine Choi-Christou, Jenny Tran, Meaghan O'Donnell, Richard A Bryant

PSYCHOLOGICAL BULLETIN | AMER PSYCHOLOGICAL ASSOC | Published : 2024

Abstract

Although trauma-focused psychotherapy (T-F psychotherapy) is the treatment of choice for posttraumatic stress disorder (PTSD), up to one half of patients do not respond to this treatment. Attempts to improve response to T-F psychotherapy have focused on augmenting fear extinction-based factors. Here, a systematic and meta-analytic review of predictors of T-F psychotherapy outcome was conducted with the goal of using an aggregate data-driven approach to elucidate baseline factors associated with treatment outcome. There were 114 studies that met inclusion criteria (N = 61, 970; Mage = 40.1 years; 40.1% female). There were 237 effect sizes across 24 meta-analytic categories. Poorer treatment r..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

This review was funded by a National Health and Medical Research Council Investigator Grant (1173921) and Grant 1073041 (Richard A. Bryant) and the Centenary of Anzac Centre (Dharani Keyan), an Australian Department of Veterans' Affairs funded initiative of Phoenix Australia. Richard A. Bryant had full access to all data and had final responsibility for the decision to submit for publication. The funders had no role in the study design, data collection, analysis, interpretation of data, writing the article, or decision to submit the review for publication. The authors declare that they have no competing interests.Open Access funding provided by University of New South Wales: This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0; https://creativecommons.org/licenses/by/4.0). This license permits copying and redistributing the work in any medium or format, as well as adapting the material for any purpose, even commercially.